Cyclosporine
FDA-approved immunosuppressant ring-shaped peptide (Neoral/Sandimmune/Restasis contexts).
What it's for
FDA-approved immunosuppressant ring-shaped peptide (Neoral/Sandimmune/Restasis contexts).
What it's for
Cyclosporine (ciclosporin) is an FDA-approved ring-shaped peptide medicine used to quiet parts of the immune system — mainly to help prevent organ transplant rejection and treat selected autoimmune conditions (eye drops/emulsions are used for dry eye, depending on the product).
What it does for the body
It prevents organ transplant rejection and treats selected autoimmune conditions; ophthalmic emulsions treat dry eye. Specific products have distinct labels. People often hear about it through clinics, forums, or news — this guide sticks to what published research and regulators actually support.
What it targets
It targets a helper protein inside immune cells (cyclophilin) and blocks calcineurin, a switch that normally turns on IL-2 (an immune messenger that helps T-cells ramp up) and activates T-cells. Dialing that down reduces the immune attack that can reject a transplant or drive some autoimmune disease.
Research context
Bottom line for readers: Cyclosporine has a defined FDA-approved story. Use the citations tab to open labels and trial registries, and treat anything beyond the label as unverified.
Studied for (literature interest)
- Immune research interest (educational tag)
Cautions (educational)
- Educational only — not medical advice.
- DrPep does not offer medical consultations, dosing guidance, suppliers, or peptide sales.
Citations / starters
- FDA search: Cyclosporine — FDA.gov search
- ClinicalTrials.gov search: Cyclosporine — U.S. clinical trials registry
- Drugs@FDA search: Cyclosporine — FDA drug database (if approved)
- PubMed search: Cyclosporine — NCBI PubMed
- PubMed Central search: Cyclosporine — NCBI PMC