Daptomycin
IV (into a vein) cyclic lipopeptide for complicated skin infections and bacteremia/endocarditis (labeled uses).
Ref $ —reference only
DaptomycinFDA-approvedWhat it's for
IV (into a vein) cyclic lipopeptide for complicated skin infections and bacteremia/endocarditis (labeled uses).
What it's for
Daptomycin is a cyclic lipopeptide antibiotic with activity against many gram-positive pathogens, including some resistant strains. It is used for complicated skin and skin-structure infections and for Staphylococcus aureus bloodstream infections including right-sided endocarditis, per labeling.
What it does for the body
It is used for complicated skin and skin-structure infections and for Staphylococcus aureus bloodstream infections including right-sided endocarditis, per labeling. It is not for pneumonia (inactivated by lung surfactant).
What it targets
Calcium-dependent insertion into the bacterial membrane causes rapid depolarization and potassium efflux, killing the organism without classic cell-wall lysis alone. Researchers map these ideas in cells and animals first; human proof has to clear a higher bar.
Research context
Bottom line for readers: Daptomycin has a defined FDA-approved story. Use the citations tab to open labels and trial registries, and treat anything beyond the label as unverified.
Studied for (literature interest)
- Skin research interest (educational tag)
Cautions (educational)
- Educational only — not medical advice.
- DrPep does not offer medical consultations, dosing guidance, suppliers, or peptide sales.
Citations / starters
- FDA search: Daptomycin — FDA.gov search
- ClinicalTrials.gov search: Daptomycin — U.S. clinical trials registry
- Drugs@FDA search: Daptomycin — FDA drug database (if approved)
- PubMed search: Daptomycin — NCBI PubMed
- PubMed Central search: Daptomycin — NCBI PMC
Reference
No ref on file.